How Lyris List Manager sends mail back to you
When you create a site (in the Server Admin Menu), you define the host name that site should identify itself as. Then, when it receives mail for that site, it will
use that name as the From: and Reply-To: names in the responding email.
Lyris List Manager supports multiple sites, which allows it to appear to the user as if several machines are each running it, and that each site (for instance, different companies) have their own
Lyris List Manager. For this reason, when mail comes in to Lyris List Manager, it needs to decide on behalf of what site the mail is for, and use the appropriate Reply-To: and From: address for that
So, it is very important that you fill in the correct machine name for each site, so that Lyris List Manager identifies itself correctly.
It is also in this way that you could have several virtual domains, each defined in their own Lyris Site, i.e., news.mycompany.com and lists.othercompany.com, etc.
For more information, see Create Site